Alprenolol hydrochloride

CAS No. 13707-88-5

Alprenolol hydrochloride( —— )

Catalog No. M22090 CAS No. 13707-88-5

Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 52 In Stock
100MG 88 In Stock
200MG 141 In Stock
500MG 316 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Alprenolol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
  • Description
    Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
  • In Vitro
    ——
  • In Vivo
    Alprenolol (p.o., 50 mg/kg) hydrochloride causes a significant drop in blood pressure which averages 20 mm Hg (at 3-hr) and an increase in heart rate by 39 beats/min (at 3-hr) in conscious renal hypertensive dogs.Alprenolol (i.p., 5 mg/kg) hydrochloride effectively blockes the anxiolytic effects of indorenate and ipsapirone but do not reduce the motor activity in adult male Swiss Webster mice.Alprenolol (intravenous injection, 0.5 or 1.0 mg/kg) can decrease systolic pressure by a mean of 10 mm Hg, diastolic pressure by a mean of 10 mm Hg) hydrochloride and heart rate by 23 beats/min, as well as slightly reduce both myocardial and liver blood flows by mean of 17% and 15% respectively at a dose of 1.0 mg/kg in cats.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT1A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13707-88-5
  • Formula Weight
    285.81
  • Molecular Formula
    C15H24ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:95 mg/mL (332.39 mM; Need ultrasonic); H2O:50 mg/mL (174.94 mM; Need ultrasonic)
  • SMILES
    Cl.CC(C)NCC(O)COc1ccccc1CC=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Millan MJ et al. Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther, 1994 Jan, 268(1):337-52.
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