Cart
sales@molnova.com
Alprenolol hydrochloride
CAS No. 13707-88-5
Alprenolol hydrochloride( —— )
Catalog No. M22090 CAS No. 13707-88-5
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 52 | In Stock |
|
| 100MG | 88 | In Stock |
|
| 200MG | 141 | In Stock |
|
| 500MG | 316 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAlprenolol hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionAlprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
-
DescriptionAlprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
-
In Vitro——
-
In VivoAlprenolol (p.o., 50 mg/kg) hydrochloride causes a significant drop in blood pressure which averages 20 mm Hg (at 3-hr) and an increase in heart rate by 39 beats/min (at 3-hr) in conscious renal hypertensive dogs.Alprenolol (i.p., 5 mg/kg) hydrochloride effectively blockes the anxiolytic effects of indorenate and ipsapirone but do not reduce the motor activity in adult male Swiss Webster mice.Alprenolol (intravenous injection, 0.5 or 1.0 mg/kg) can decrease systolic pressure by a mean of 10 mm Hg, diastolic pressure by a mean of 10 mm Hg) hydrochloride and heart rate by 23 beats/min, as well as slightly reduce both myocardial and liver blood flows by mean of 17% and 15% respectively at a dose of 1.0 mg/kg in cats.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor5-HT1A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number13707-88-5
-
Formula Weight285.81
-
Molecular FormulaC15H24ClNO2
-
Purity>98% (HPLC)
-
SolubilityDMSO:95 mg/mL (332.39 mM; Need ultrasonic); H2O:50 mg/mL (174.94 mM; Need ultrasonic)
-
SMILESCl.CC(C)NCC(O)COc1ccccc1CC=C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Millan MJ et al. Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther, 1994 Jan, 268(1):337-52.
molnova catalog
related products
-
17α-Estradiol
Endogenous estrogen receptor ligand (Ki?values are 0.2 and 1.2 nM for ERα?and ERβ?receptors respectively).
-
Chlorpromazine hydro...
Chlorpromazine hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
-
Granisetron hydrochl...
Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
